Dermoplex Calamine Cream is a skin-soothing and barrier-protecting formula. In cases of skin irritation, itching, or sunburn, this lotion can be a lifesaver. Minor skin irritations and rashes can be soothed with the use of this solution (sunburn, prickly heat, insect bites, itchy chicken pox and nappy rashes). Calamine evaporates from the skin after application, resulting in a cooling sensation that helps alleviate the itch. An added benefit of this sensation is that it soothes sunburns. Zinc oxide, which is antimicrobial, is also an active ingredient in this lotion. This makes the skin feel calm and prevents infections from scratching.